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Group B Streptococcus (GBS) is one of the major causes of severe maternal and neonatal infections and sepsis.
Prevention
Tests generally appear in the order most useful for common clinical situations
| Test name: Cerebrospinal Fluid (CSF) Culture and Gram Stain |
| ARUP #: 0060106 |
| Methodology: Stain/Culture/Identification |
| Use: Identify agent of presumed meningitis |
| Test name: Protein, Total, CSF |
| ARUP #: 0020514 |
| Methodology: Reflectance Spectrophotometry |
| Use: Help differentiate viral from bacterial source |
| Test name: Glucose, CSF |
| ARUP #: 0020515 |
| Methodology: Enzymatic |
| Use: Help differentiate viral from bacterial source |
| Test name: CBC with Platelet Count and Automated Differential |
| ARUP #: 0040003 |
| Methodology: Automated Cell Count/Differential |
| Use: Initial test for infection |
| Test name: Streptococcus Group B by PCR |
| ARUP #: 0060705 |
| Methodology: Qualitative Polymerase Chain Reaction |
| Use: Determine genital and rectal colonization status in adults Screen pregnant women at 35-37 weeks |
| Limitations: Low rate of colonization gives false-negative results |
| Follow-up: If negative and high suspicion for GBS, perform culture |
| Test name: Body Fluid Culture and Gram Stain |
| ARUP #: 0060108 |
| Methodology: Stain/Culture/Identification |
| Use: Determine whether GBS is organism causing infection |
| Test name: Wound Culture and Gram Stain |
| ARUP #: 0060132 |
| Methodology: Stain/Culture/Identification |
| Use: Determine whether GBS is organism causing infection |
| Test name: C-Reactive Protein, Neonatal |
| ARUP #: 0050181 |
| Methodology: Immunoassay |
| Comments: May be helpful in evaluation of neonatal sepsis; cannot be used for infants of very low birth weight 6- and 12-hour samples required |
| Test name: Procalcitonin |
| ARUP #: 0020763 |
| Methodology: Immunofluorescence |
| Comments: Evaluate late-onset sepsis |