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Hepatic proteins refer to a group of proteins synthesized in the liver that may be used in the assessment of nutritional status. Hepatic proteins include the following
Tests generally appear in the order most useful for common clinical situations
| Test name: Albumin, Serum or Plasma by Spectrophotometry |
| ARUP #: 0020030 |
| Methodology: Quantitative Spectrophotometry |
| Use: Evaluate production of albumin by liver; assess nutritional status Assess nephrotic syndrome and protein-losing enteropathy |
| Limitations: Albumin may be acutely decreased in sepsis or trauma |
| Test name: Prealbumin, Serum |
| ARUP #: 0050435 |
| Methodology: Immunoturbidimetric |
| Use: Assess nutritional status in premature infants, in cancer patients and surgical patients Recommended protein measurement to evaluate nutritional status in hospitalized patients Assess nephrotic syndrome and protein-losing enteropathy |
| Limitations: Prealbumin may be acutely decreased in sepsis or trauma |
| Test name: Retinol Binding Protein |
| ARUP #: 0050467 |
| Methodology: Quantitative Nephelometry |
| Use: Indicate early malnutrition, acute and chronic hepatitic disease, advanced chronic renal insufficiency and cystic fibrosis Assess nephrotic syndrome and protein-losing enteropathy |
| Test name: Transferrin, Serum |
| ARUP #: 0050570 |
| Methodology: Quantitative Immunoturbidimetric |
| Use: Aid in differential diagnosis of malnutrition Monitor iron deficiency anemia |
| Test name: Alpha-1-Antitrypsin, Feces |
| ARUP #: 0099991 |
| Methodology: Quantitative Radial Immunodiffusion |
| Use: Order as a follow-up test when protein-losing enteropathy is suspected Serves as a clearance measure; calculations require that serum alpha-1-antitrypsin test also be ordered |
| Limitations: Blood in stool or diarrhea may increase clearance |
| Test name: Alpha-1-Antitrypsin |
| ARUP #: 0050001 |
| Methodology: Quantitative Immunoturbidimetric |
| Use: Calculations for the alpha-1-antitrypsin fecal test require that this test also be ordered |