Nephrolithiasis is a worldwide problem that accounts for significant morbidity and expense.
Tests generally appear in the order most useful for common clinical situations
| Test name: CBC with Platelet Count & Automated Differential |
| ARUP #: 0040003 |
| Methodology: Automated Cell Count with Flow Cell Differential |
| Use: Rule out concomitant infection |
| Test name: Electrolyte Panel |
| ARUP #: 0020410 |
| Methodology: Quantitative Ion-Selective Electrode/Enzymatic |
| Use: Rule out electrolyte abnormalities associated with vomiting |
| Test name: Urinalysis, Complete |
| ARUP #: 0020350 |
| Methodology: Reflective Photometry/Microscopic by Yellow IRIS |
| Use: Detect urinary tract abnormalities including crystals |
| Test name: Urine Supersaturation Profile |
| ARUP #: 0081145 |
| Methodology: Refer to individual components |
| Use: Profile tests for calcium, magnesium, sodium, sulfate, citric acid, oxalate, uric acid, potassium, creatinine (24-hour) chloride and phosphorous Predict formation of calcium oxalate, calcium hydrogen phosphate and/or uric acid calculi Monitor renal stone disease after initiation of therapy |
| Limitations: Assessment for risk of magnesium ammonium phosphate (struvite) calculi is not included in this profile Does not test for urine cystine |
| Follow-up: If magnesium ammonium phosphate calculi are suspected, order plasma ammonia testing If cystine calculi are suspected, order cystinuria panel, cystine quantitative urine or amino acids quantitative urine tests |
| Test name: Cystinuria Panel |
| ARUP #: 0081105 |
| Methodology: Ion Exchange Chromatography |
| Use: Evaluate for cystinuria Panel includes arginine, cystine, lysine and ornithine |
| Test name: Cystine Quantitative, Urine |
| ARUP #: 0081106 |
| Methodology: Liquid Chromatography/Tandem Mass Spectrometry |
| Use: Monitor treatment in patients with cystinuria |
| Test name: Amino Acids Quantitative, Urine |
| ARUP #: 0080044 |
| Methodology: Ion Exchange Chromatography |
| Use: Use for risk assessment if cystine stone is found |
| Test name: Calculi (Stone) Analysis with Photo |
| ARUP #: 2005231 |
| Methodology: Quantitative Reflectance Fourier Transform Infrared Spectroscopy (FTIR)/Quantitative Polarizing Microscopy |
| Use: Determine composition of calculi Determine causative agent of calculi |
| Test name: Kidney Stone Risk Panel, Urine |
| ARUP #: 0020843 |
| Methodology: Refer to individual components |
| Comments: Preferred test is urine supersaturation profile |
| Test name: Kidney Stone Risk Panel II, Urine |
| ARUP #: 0020805 |
| Methodology: Refer to individual components |
| Comments: Tests for calcium, chloride, citric acid, cystine, magnesium, oxalate, phosphorous, potassium, sodium |
| Test name: Creatinine, Serum or Plasma |
| ARUP #: 0020025 |
| Methodology: Quantitative Enzymatic |
| Comments: |
| Test name: Creatinine, 24-Hour Urine |
| ARUP #: 0020473 |
| Methodology: Quantitative Spectrophotometry |
| Comments: |
| Test name: Oxalate, Urine |
| ARUP #: 0020482 |
| Methodology: Quantitative Spectrophotometry |
| Comments: |
| Test name: Citric Acid, Urine |
| ARUP #: 0020852 |
| Methodology: Quantitative Enzymatic |
| Comments: |
| Test name: Urea Nitrogen, Serum or Plasma |
| ARUP #: 0020023 |
| Methodology: Quantitative Spectrophotometry |
| Comments: |
| Test name: Uric Acid, Serum or Plasma |
| ARUP #: 0020026 |
| Methodology: Quantitative Spectrophotometry |
| Comments: |
| Test name: Calcium, Ionized, Serum |
| ARUP #: 0020135 |
| Methodology: Ion-Selective Electrode/pH-Electrode |
| Comments: |
| Test name: Parathyroid Hormone-Related Peptide (PTHrP) |
| ARUP #: 0093014 |
| Methodology: Quantitative Immunoradiometric Assay |
| Comments: |