Infertility is a common problem in the U.S. affecting millions of couples who incur significant expense for fertility treatments.
Tests generally appear in the order most useful for common clinical situations
| Test name: Luteinizing Hormone and Follicle Stimulating Hormone |
| ARUP #: 0070193 |
| Methodology: Quantitative Electrochemiluminescent Immunoassay |
| Use: Determine etiology if ovulatory or androgen dysfunction suspected |
| Test name: Progesterone |
| ARUP #: 0070110 |
| Methodology: Chemiluminescent Immunoassay |
| Use: Determine if progesterone associated with ovulatory dysfunction |
| Test name: Prolactin |
| ARUP #: 0070115 |
| Methodology: Quantitative Chemiluminescent Immunoassay |
| Use: Determine if elevated prolactin is cause of infertility |
| Test name: Macroprolactin |
| ARUP #: 0020765 |
| Methodology: Quantitative Chemiluminescent Immunoassay |
| Use: Exclude prolactinoma |
| Test name: 17-Hydroxyprogesterone |
| ARUP #: 0070005 |
| Methodology: Quantitative Radioimmunoassay |
| Use: Assist in determining etiology of infertility |
| Test name: Thyroid Stimulating Hormone |
| ARUP #: 0070145 |
| Methodology: Quantitative Electrochemiluminescent Immunoassay |
| Use: Determine thyroid function |
| Test name: Testosterone Free, Females or Children |
| ARUP #: 0081059 |
| Methodology: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry/Electrochemiluminescent Immunoassay The concentration of free testosterone is derived from a mathematical expression based on the constant for the binding of testosterone to sex hormone binding globulin. |
| Use: Assess for hyperandrogenism or PCOS |
| Limitations: Test is suggested for women and children due to an improved sensitivity of testosterone by LC-MS/MS |
| Test name: Anti-Mullerian Hormone |
| ARUP #: 2002656 |
| Methodology: Quantitative Enzyme-Linked Immunosorbent Assay |
| Use: Estimate ovarian reserve Diagnose PCOS |
| Test name: Estradiol, Adult Premenopausal Female, Serum or Plasma |
| ARUP #: 0070045 |
| Methodology: Quantitative Chemiluminescent Immunoassay |
| Use: Estimate ovarian reserve |
| Test name: Y Chromosome Microdeletion |
| ARUP #: 2001778 |
| Methodology: Polymerase Chain Reaction/Electrophoresis |
| Use: Determine etiology of azoospermia or severe oligospermia |
| Test name: Chromosome Analysis, Peripheral Blood |
| ARUP #: 2002289 |
| Methodology: Giemsa-Band Analysis |
| Use: Diagnose Klinefelter syndrome Detect structural abnormalities of the Y chromosome associated with male infertility |
| Test name: Cystic Fibrosis (CFTR) Sequencing |
| ARUP #: 0051110 |
| Methodology: Polymerase Chain Reaction/Scanning/Sequencing |
| Use: Screen for cystic fibrosis mutations in males with congenital bilateral absence of the vas deferens |
| Test name: CBC with Platelet Count & Automated Differential |
| ARUP #: 0040003 |
| Methodology: Automated Cell Count with Flow Cell Differential |
| Use: Rule out infection |
| Test name: Gonorrhea Culture |
| ARUP #: 0060110 |
| Methodology: Standard reference procedures for N. gonorrhoeae culture and identification |
| Use: Rule out STI |
| Test name: Chlamydia trachomatis Culture |
| ARUP #: 0060850 |
| Methodology: Cell Culture/Immunofluorescence |
| Use: Rule out STI |
| Test name: Urinalysis, Complete |
| ARUP #: 0020350 |
| Methodology: Reflective Photometry/Microscopic by Yellow IRIS |
| Use: Rule out infection |
| Test name: Testosterone, Females or Children |
| ARUP #: 0081058 |
| Methodology: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry |
| Comments: |
| Test name: Testosterone, Free & Total (Includes Sex Hormone Binding Globulin), Females or Children |
| ARUP #: 0081056 |
| Methodology: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry/Electrochemiluminescent Immunoassay The concentration of free testosterone is derived from a mathematical expression based on the constant for the binding of testosterone to sex hormone binding globulin. |
| Comments: |
| Test name: Testosterone, Bioavailable & Sex Hormone Binding Globulin (Includes Total Testosterone), Females or Children |
| ARUP #: 0081057 |
| Methodology: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry/Electrochemiluminescent Immunoassay The concentrations of free and bioavailable testosterone are derived from mathematical expressions based on constants for the binding of testosterone to albumin and/or sex hormone binding globulin. |
| Comments: |
| Test name: Inhibin B |
| ARUP #: 0070413 |
| Methodology: Quantitative Enzyme-Linked Immunosorbent Assay |
| Comments: |
| Test name: Follicle Stimulating Hormone, Serum |
| ARUP #: 0070055 |
| Methodology: Quantitative Electrochemiluminescent Immunoassay |
| Comments: |
| Test name: Estriol, Serum |
| ARUP #: 0070051 |
| Methodology: Quantitative Chemiluminescent Immunoassay |
| Comments: |