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Hantavirus causes hantavirus pulmonary syndrome (HPS) and was first reported in the Americas. Hemorrhagic fever with renal syndrome (HFRS) was first reported in Asia and Europe in 1993.
Tests generally appear in the order most useful for common clinical situations
| Test name: CBC with Platelet Count & Automated Differential |
| ARUP #: 0040003 |
| Methodology: Automated Cell Count with Flow Cell Differential |
| Use: Assist in ruling out bacterial infection |
| Test name: Hepatic Function Panel |
| ARUP #: 0020416 |
| Methodology: Refer to individual components. |
| Use: Rule out hepatic involvement |
| Test name: Prothrombin Time |
| ARUP #: 0030215 |
| Methodology: Electromagnetic Mechanical Clot Detection |
| Use: Initial testing to rule out coagulopathy |
| Test name: Partial Thromboplastin Time |
| ARUP #: 0030235 |
| Methodology: Electromagnetic Mechanical Clot Detection |
| Use: Initial testing to rule out coagulopathy |
| Test name: Hantavirus Antibodies, IgG and IgM with Reflex to Confirmation |
| ARUP #: 2001540 |
| Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay |
| Use: Detect hantavirus-specific IgG and IgM in serum samples with a clinical suspicion of HPS or HFRS If screen is positive, confirmation will be added |
| Limitations: False positives occur in cytomegalovirus, influenza and Mycoplasma pneumoniae infection |
| Follow-up: If test results are equivocal, repeat testing in 10-14 days |